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YM155 Inhibits Topoisomerase Function
YM155 (Sepantronium bromide) has been evaluated in clinical trials as a survivin suppressant but despite positive signals from early work later studies were negative. Clarifying the mechanism of action of YM155 is important to its further development. YM155 affects cells in a cell cycle specific man...
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| Veröffentlicht in: | Anticancer Drugs |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225247/ https://ncbi.nlm.nih.gov/pubmed/27754993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0000000000000441 |
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