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YM155 Inhibits NleB and SseK Arginine Glycosyltransferase Activity
The type III secretion system effector proteins NleB and SseK are glycosyltransferases that glycosylate protein substrates on arginine residues. We conducted high-throughput screening assays on 42,498 compounds to identify NleB/SseK inhibitors. Such small molecules may be useful as mechanistic probe...
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| Pubblicato in: | Pathogens |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7926936/ https://ncbi.nlm.nih.gov/pubmed/33672424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens10020253 |
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