Adipose Fatty Acid Binding Protein Promotes Saturated Fatty Acid-induced Macrophage Cell Death through Enhancing Ceramide Production

Macrophages play a critical role in obesity-associated chronic inflammation and disorders. However, the molecular mechanisms underlying the response of macrophages to elevated fatty acids (FAs) and their contribution to metabolic inflammation in obesity remain to be fully elucidated. Here, we report...

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Udgivet i:J Immunol
Main Authors: Zhang, Yuwen, Rao, Enyu, Zeng, Jun, Hao, Jiaqing, Sun, Yanwen, Liu, Shujun, Sauter, Edward R., Bernlohr, David A., Cleary, Margot P., Suttles, Jill, Li, Bing
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225136/
https://ncbi.nlm.nih.gov/pubmed/27920274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601403
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