Adipose Fatty Acid Binding Protein Promotes Saturated Fatty Acid-induced Macrophage Cell Death through Enhancing Ceramide Production

Macrophages play a critical role in obesity-associated chronic inflammation and disorders. However, the molecular mechanisms underlying the response of macrophages to elevated fatty acids (FAs) and their contribution to metabolic inflammation in obesity remain to be fully elucidated. Here, we report...

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Veröffentlicht in:J Immunol
Hauptverfasser: Zhang, Yuwen, Rao, Enyu, Zeng, Jun, Hao, Jiaqing, Sun, Yanwen, Liu, Shujun, Sauter, Edward R., Bernlohr, David A., Cleary, Margot P., Suttles, Jill, Li, Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225136/
https://ncbi.nlm.nih.gov/pubmed/27920274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601403
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