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Fatty acid binding protein E-FABP restricts tumor growth by promoting IFNβ responses in tumor-associated macrophages

Fatty acid binding proteins (FABPs) are known central regulators of both metabolic and inflammatory pathways, but their role in tumor development remains largely unexplored. Here, we report that host expression of epidermal FABP (E-FABP) protects against mammary tumor growth. We find that E-FABP is...

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Detalhes bibliográficos
Main Authors: Zhang, Yuwen, Sun, Yanwen, Rao, Enyu, Yan, Fei, Li, Qiang, Zhang, Ying, Silverstein, Kevin A. T., Liu, Shujun, Sauter, Edward, Cleary, Margot P., Li, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040301/
https://ncbi.nlm.nih.gov/pubmed/24713431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2689
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