Stearic acid induces CD11c expression in proinflammatory macrophages via epidermal fatty acid binding protein

Obesity is associated with elevated levels of free fatty acids (FFAs) and pro-inflammatory CD11c+ macrophages. However, whether and how FFAs contribute to CD11c+ macrophage differentiation and pro-inflammatory functions remain unclear. Here we report that dietary saturated FAs, but not unsaturated F...

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Veröffentlicht in:J Immunol
Hauptverfasser: Zeng, Jun, Zhang, Yuwen, Hao, Jiaqing, Sun, Yanwen, Liu, Shujun, Bernlohr, David A., Sauter, Edward R., Cleary, Margot P., Suttles, Jill, Li, Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940522/
https://ncbi.nlm.nih.gov/pubmed/29626089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701416
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