Screening for ROS1 gene rearrangements in non-small cell lung cancers using immunohistochemistry with FISH confirmation is an effective method to identify this rare target

AIMS: To assess the prevalence of ROS1 rearrangements in a retrospective and prospective diagnostic Australian cohort and evaluate the effectiveness of immunohistochemical screening. METHODS: A retrospective cohort of 278 early stage lung adenocarcinomas and an additional 104 prospective NSCLC cases...

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Detalhes bibliográficos
Publicado no:Histopathology
Main Authors: Selinger, Christina I, Li, Bob T, Pavlakis, Nick, Links, Matthew, Gill, Anthony J, Lee, Adrian, Clarke, Stephen, Tran, Thang N, Lum, Trina, Yip, Po Yee, Horvath, Lisa, Yu, Bing, Kohonen-Corish, Maija RJ, O’Toole, Sandra A, Cooper, Wendy A
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225047/
https://ncbi.nlm.nih.gov/pubmed/27599111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/his.13076
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