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Amplification of the HER2 gene in breast cancers testing 2+ weak positive by HercepTest immunohistochemistry: false‐positive or false‐negative immunohistochemistry?

BACKGROUND: The majority of cases of breast cancer scoring HER2 weak positive (2+) on immunohistochemistry (IHC) using the HercepTest are not associated with amplification of the HER2/neu gene. AIM: To examine the reproducibility of IHC in cases scoring 2+ subsequently shown to have gene amplificati...

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Detaylı Bibliyografya
Asıl Yazarlar: Barrett, Ciara, Magee, Hilary, O'Toole, Denise, Daly, Sinead, Jeffers, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Group 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955078/
https://ncbi.nlm.nih.gov/pubmed/16822876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2006.039602
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