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Amplification of the HER2 gene in breast cancers testing 2+ weak positive by HercepTest immunohistochemistry: false‐positive or false‐negative immunohistochemistry?
BACKGROUND: The majority of cases of breast cancer scoring HER2 weak positive (2+) on immunohistochemistry (IHC) using the HercepTest are not associated with amplification of the HER2/neu gene. AIM: To examine the reproducibility of IHC in cases scoring 2+ subsequently shown to have gene amplificati...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1955078/ https://ncbi.nlm.nih.gov/pubmed/16822876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2006.039602 |
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