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Decarboxylative Peptide Macrocyclization via Photoredox Catalysis

A method for the decarboxylative macrocyclization of peptides bearing N-terminal Michael acceptors has been developed. This synthetic protocol enables the efficient synthesis of γ-amino acid-containing cyclic peptides and is tolerant of functionality present in both natural and non-proteinogenic ami...

詳細記述

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書誌詳細
出版年:Angew Chem Int Ed Engl
主要な著者: McCarver, Stefan J., Qiao, Jennifer X., Carpenter, Joseph, Borzilleri, Robert M., Poss, Michael A., Eastgate, Martin D., Miller, Michael, MacMillan, David W. C.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225041/
https://ncbi.nlm.nih.gov/pubmed/27860140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201608207
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