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Decarboxylative Peptide Macrocyclization via Photoredox Catalysis
A method for the decarboxylative macrocyclization of peptides bearing N-terminal Michael acceptors has been developed. This synthetic protocol enables the efficient synthesis of γ-amino acid-containing cyclic peptides and is tolerant of functionality present in both natural and non-proteinogenic ami...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225041/ https://ncbi.nlm.nih.gov/pubmed/27860140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201608207 |
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