Thermotoga maritima NusG: domain interaction mediates autoinhibition and thermostability

NusG, the only universally conserved transcription factor, comprises an N- and a C-terminal domain (NTD, CTD) that are flexibly connected and move independently in Escherichia coli and other organisms. In NusG from the hyperthermophilic bacterium Thermotoga maritima (tmNusG), however, NTD and CTD in...

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Foilsithe in:Nucleic Acids Res
Main Authors: Drögemüller, Johanna, Schneider, Christin, Schweimer, Kristian, Strauß, Martin, Wöhrl, Birgitta M., Rösch, Paul, Knauer, Stefan H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2017
Ábhair:
Structural Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224480/
https://ncbi.nlm.nih.gov/pubmed/27899597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1111
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