Thermotoga maritima NusG: domain interaction mediates autoinhibition and thermostability

NusG, the only universally conserved transcription factor, comprises an N- and a C-terminal domain (NTD, CTD) that are flexibly connected and move independently in Escherichia coli and other organisms. In NusG from the hyperthermophilic bacterium Thermotoga maritima (tmNusG), however, NTD and CTD in...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Drögemüller, Johanna, Schneider, Christin, Schweimer, Kristian, Strauß, Martin, Wöhrl, Birgitta M., Rösch, Paul, Knauer, Stefan H.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
Structural Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224480/
https://ncbi.nlm.nih.gov/pubmed/27899597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1111
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