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Thermotoga maritima NusG: domain interaction mediates autoinhibition and thermostability

NusG, the only universally conserved transcription factor, comprises an N- and a C-terminal domain (NTD, CTD) that are flexibly connected and move independently in Escherichia coli and other organisms. In NusG from the hyperthermophilic bacterium Thermotoga maritima (tmNusG), however, NTD and CTD in...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Drögemüller, Johanna, Schneider, Christin, Schweimer, Kristian, Strauß, Martin, Wöhrl, Birgitta M., Rösch, Paul, Knauer, Stefan H.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224480/
https://ncbi.nlm.nih.gov/pubmed/27899597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1111
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