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Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators

NusG is a conserved regulatory protein that interacts with elongating complexes (ECs) of RNA polymerase (RNAP), DNA, and RNA to modulate transcription in multiple and sometimes opposite ways. In E. coli, NusG suppresses pausing and increases elongation rate, enhances termination by E. coli ρ and pha...

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Hlavní autoři: Mooney, Rachel Anne, Schweimer, Kristian, Roesch, Paul, Gottesman, Max, Landick, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763281/
https://ncbi.nlm.nih.gov/pubmed/19500594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.05.078
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