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Rho and NusG suppress pervasive antisense transcription in Escherichia coli

Despite the prevalence of antisense transcripts in bacterial transcriptomes, little is known about how their synthesis is controlled. We report that a major function of the Escherichia coli termination factor Rho and its cofactor, NusG, is suppression of ubiquitous antisense transcription genome-wid...

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Bibliographic Details
Main Authors: Peters, Jason M., Mooney, Rachel A., Grass, Jeffrey A., Jessen, Erik D., Tran, Frances, Landick, Robert
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521622/
https://ncbi.nlm.nih.gov/pubmed/23207917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.196741.112
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