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Termination Factor Rho and Its Cofactors NusA and NusG Silence Foreign DNA in E. coli

Transcription of the bacterial genome by the RNA polymerase must terminate at specific points. Transcription can be terminated by Rho factor, an essential protein in enterobacteria. We utilized the antibiotic bicyclomycin, which inhibits Rho, to assess its role on a genome-wide scale. Rho is a globa...

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Bibliografiska uppgifter
Huvudupphovsmän: Cardinale, Christopher J., Washburn, Robert S., Tadigotla, Vasisht R., Brown, Lewis M., Gottesman, Max E., Nudler, Evgeny
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059013/
https://ncbi.nlm.nih.gov/pubmed/18487194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1152763
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