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Termination Factor Rho and Its Cofactors NusA and NusG Silence Foreign DNA in E. coli

Transcription of the bacterial genome by the RNA polymerase must terminate at specific points. Transcription can be terminated by Rho factor, an essential protein in enterobacteria. We utilized the antibiotic bicyclomycin, which inhibits Rho, to assess its role on a genome-wide scale. Rho is a globa...

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Библиографические подробности
Главные авторы: Cardinale, Christopher J., Washburn, Robert S., Tadigotla, Vasisht R., Brown, Lewis M., Gottesman, Max E., Nudler, Evgeny
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059013/
https://ncbi.nlm.nih.gov/pubmed/18487194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1152763
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