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Termination Factor Rho and Its Cofactors NusA and NusG Silence Foreign DNA in E. coli

Transcription of the bacterial genome by the RNA polymerase must terminate at specific points. Transcription can be terminated by Rho factor, an essential protein in enterobacteria. We utilized the antibiotic bicyclomycin, which inhibits Rho, to assess its role on a genome-wide scale. Rho is a globa...

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Detalhes bibliográficos
Main Authors: Cardinale, Christopher J., Washburn, Robert S., Tadigotla, Vasisht R., Brown, Lewis M., Gottesman, Max E., Nudler, Evgeny
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059013/
https://ncbi.nlm.nih.gov/pubmed/18487194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1152763
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