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Two distinct membrane potential–dependent steps drive mitochondrial matrix protein translocation

Two driving forces energize precursor translocation across the inner mitochondrial membrane. Although the membrane potential (Δψ) is considered to drive translocation of positively charged presequences through the TIM23 complex (presequence translocase), the activity of the Hsp70-powered import moto...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Schendzielorz, Alexander Benjamin, Schulz, Christian, Lytovchenko, Oleksandr, Clancy, Anne, Guiard, Bernard, Ieva, Raffaele, van der Laan, Martin, Rehling, Peter
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223606/
https://ncbi.nlm.nih.gov/pubmed/28011846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607066
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