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Two distinct membrane potential–dependent steps drive mitochondrial matrix protein translocation

Two driving forces energize precursor translocation across the inner mitochondrial membrane. Although the membrane potential (Δψ) is considered to drive translocation of positively charged presequences through the TIM23 complex (presequence translocase), the activity of the Hsp70-powered import moto...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Schendzielorz, Alexander Benjamin, Schulz, Christian, Lytovchenko, Oleksandr, Clancy, Anne, Guiard, Bernard, Ieva, Raffaele, van der Laan, Martin, Rehling, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223606/
https://ncbi.nlm.nih.gov/pubmed/28011846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607066
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