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Presequence Recognition by the Tom40 Channel Contributes to Precursor Translocation into the Mitochondrial Matrix

More than 70% of mitochondrial proteins utilize N-terminal presequences as targeting signals. Presequence interactions with redundant cytosolic receptor domains of the translocase of the outer mitochondrial membrane (TOM) are well established. However, after the presequence enters the protein-conduc...

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Main Authors: Melin, Jonathan, Schulz, Christian, Wrobel, Lidia, Bernhard, Olaf, Chacinska, Agnieszka, Jahn, Olaf, Schmidt, Bernhard, Rehling, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135617/
https://ncbi.nlm.nih.gov/pubmed/25002531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00433-14
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