Distinct Forms of Mitochondrial TOM-TIM Supercomplexes Define Signal-Dependent States of Preprotein Sorting

Mitochondrial import of cleavable preproteins occurs at translocation contact sites, where the translocase of the outer membrane (TOM) associates with the presequence translocase of the inner membrane (TIM23) in a supercomplex. Different views exist on the mechanism of how TIM23 mediates preprotein...

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Main Authors: Chacinska, Agnieszka, van der Laan, Martin, Mehnert, Carola S., Guiard, Bernard, Mick, David U., Hutu, Dana P., Truscott, Kaye N., Wiedemann, Nils, Meisinger, Chris, Pfanner, Nikolaus, Rehling, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798301/
https://ncbi.nlm.nih.gov/pubmed/19884344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00749-09
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