Distinct Forms of Mitochondrial TOM-TIM Supercomplexes Define Signal-Dependent States of Preprotein Sorting

Mitochondrial import of cleavable preproteins occurs at translocation contact sites, where the translocase of the outer membrane (TOM) associates with the presequence translocase of the inner membrane (TIM23) in a supercomplex. Different views exist on the mechanism of how TIM23 mediates preprotein...

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Hlavní autoři: Chacinska, Agnieszka, van der Laan, Martin, Mehnert, Carola S., Guiard, Bernard, Mick, David U., Hutu, Dana P., Truscott, Kaye N., Wiedemann, Nils, Meisinger, Chris, Pfanner, Nikolaus, Rehling, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798301/
https://ncbi.nlm.nih.gov/pubmed/19884344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00749-09
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