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Inferring Heterozygosity from Ancient and Low Coverage Genomes

While genetic diversity can be quantified accurately from high coverage sequencing data, it is often desirable to obtain such estimates from data with low coverage, either to save costs or because of low DNA quality, as is observed for ancient samples. Here, we introduce a method to accurately infer...

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Publicat a:Genetics
Autors principals: Kousathanas, Athanasios, Leuenberger, Christoph, Link, Vivian, Sell, Christian, Burger, Joachim, Wegmann, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223511/
https://ncbi.nlm.nih.gov/pubmed/27821432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.189985
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