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A Novel Approach to Estimating Heterozygosity from Low-Coverage Genome Sequence
High-throughput shotgun sequence data make it possible in principle to accurately estimate population genetic parameters without confounding by SNP ascertainment bias. One such statistic of interest is the proportion of heterozygous sites within an individual’s genome, which is informative about inb...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3781980/ https://ncbi.nlm.nih.gov/pubmed/23934885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.154500 |
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