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Estimation of Allele Frequencies From High-Coverage Genome-Sequencing Projects

A new generation of high-throughput sequencing strategies will soon lead to the acquisition of high-coverage genomic profiles of hundreds to thousands of individuals within species, generating unprecedented levels of information on the frequencies of nucleotides segregating at individual sites. Howe...

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Detalles Bibliográficos
Autor Principal: Lynch, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674824/
https://ncbi.nlm.nih.gov/pubmed/19293142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.100479
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