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Inferring Heterozygosity from Ancient and Low Coverage Genomes

While genetic diversity can be quantified accurately from high coverage sequencing data, it is often desirable to obtain such estimates from data with low coverage, either to save costs or because of low DNA quality, as is observed for ancient samples. Here, we introduce a method to accurately infer...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Kousathanas, Athanasios, Leuenberger, Christoph, Link, Vivian, Sell, Christian, Burger, Joachim, Wegmann, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223511/
https://ncbi.nlm.nih.gov/pubmed/27821432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.189985
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