MT5-MMP Promotes Alzheimer’s Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro

We previously reported that deficiency of membrane-type five matrix metalloproteinase (MT5-MMP) prevents amyloid pathology in the cortex and hippocampus of 5xFAD mice, and ameliorates the functional outcome. We have now investigated whether the integrity of another important area affected in Alzheim...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Baranger, Kévin, Bonnet, Amandine E., Girard, Stéphane D., Paumier, Jean-Michel, García-González, Laura, Elmanaa, Wejdane, Bernard, Anne, Charrat, Eliane, Stephan, Delphine, Bauer, Charlotte, Moschke, Katrin, Lichtenthaler, Stefan F., Roman, François S., Checler, Frédéric, Khrestchatisky, Michel, Rivera, Santiago
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223243/
https://ncbi.nlm.nih.gov/pubmed/28119565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00163
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados