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Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer’s disease: Alleviation by pantethine

Astrocytes play critical roles in central nervous system homeostasis and support of neuronal function. A better knowledge of their response may both help understand the pathophysiology of Alzheimer’s disease (AD) and implement new therapeutic strategies. We used the 5xFAD transgenic mouse model of A...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: van Gijsel-Bonnello, Manuel, Baranger, Kévin, Benech, Philippe, Rivera, Santiago, Khrestchatisky, Michel, de Reggi, Max, Gharib, Bouchra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391924/
https://ncbi.nlm.nih.gov/pubmed/28410378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175369
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