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Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer’s disease: Alleviation by pantethine

Astrocytes play critical roles in central nervous system homeostasis and support of neuronal function. A better knowledge of their response may both help understand the pathophysiology of Alzheimer’s disease (AD) and implement new therapeutic strategies. We used the 5xFAD transgenic mouse model of A...

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Publicado en:PLoS One
Autores principales: van Gijsel-Bonnello, Manuel, Baranger, Kévin, Benech, Philippe, Rivera, Santiago, Khrestchatisky, Michel, de Reggi, Max, Gharib, Bouchra
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391924/
https://ncbi.nlm.nih.gov/pubmed/28410378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175369
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