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Proteome-Scale Investigation of Protein Allosteric Regulation Perturbed by Somatic Mutations in 7,000 Cancer Genomes
The allosteric regulation triggering the protein’s functional activity via conformational changes is an intrinsic function of protein under many physiological and pathological conditions, including cancer. Identification of the biological effects of specific somatic variants on allosteric proteins a...
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| Yayımlandı: | Am J Hum Genet |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223033/ https://ncbi.nlm.nih.gov/pubmed/27939638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.09.020 |
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