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Proteome-Scale Investigation of Protein Allosteric Regulation Perturbed by Somatic Mutations in 7,000 Cancer Genomes
The allosteric regulation triggering the protein’s functional activity via conformational changes is an intrinsic function of protein under many physiological and pathological conditions, including cancer. Identification of the biological effects of specific somatic variants on allosteric proteins a...
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| Publicado no: | Am J Hum Genet |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223033/ https://ncbi.nlm.nih.gov/pubmed/27939638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.09.020 |
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