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Proteome-Scale Investigation of Protein Allosteric Regulation Perturbed by Somatic Mutations in 7,000 Cancer Genomes

The allosteric regulation triggering the protein’s functional activity via conformational changes is an intrinsic function of protein under many physiological and pathological conditions, including cancer. Identification of the biological effects of specific somatic variants on allosteric proteins a...

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Bibliografski detalji
Izdano u:Am J Hum Genet
Glavni autori: Shen, Qiancheng, Cheng, Feixiong, Song, Huili, Lu, Weiqiang, Zhao, Junfei, An, Xiaoli, Liu, Mingyao, Chen, Guoqiang, Zhao, Zhongming, Zhang, Jian
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223033/
https://ncbi.nlm.nih.gov/pubmed/27939638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.09.020
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