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Caspase Inhibition Prevents Tumor Necrosis Factor-α–Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in Vivo and in Vitro
How different cell death modes and cell survival pathways cross talk remains elusive. We determined the interrelation of apoptosis, necrosis, and autophagy in tumor necrosis factor (TNF)-α/actinomycin D (ActD) and lipopolysaccharide/D-galactosamine (GalN)-induced hepatotoxicity in vitro and in vivo....
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Udgivet i: | Am J Pathol |
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Main Authors: | , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Investigative Pathology
2016
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5222974/ https://ncbi.nlm.nih.gov/pubmed/27616656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.06.009 |
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