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Mechanisms of Acetaminophen-induced Cell Death in Primary Human Hepatocytes

Acetaminophen (APAP) overdose is the most prevalent cause of drug-induced liver injury in western countries. Numerous studies have been conducted to investigate the mechanisms of injury after APAP overdose in various animal models; however, the importance of these mechanisms for humans remains uncle...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Xie, Yuchao, McGill, Mitchell R., Dorko, Kenneth, Kumer, Sean C., Schmitt, Timothy M., Forster, Jameson, Jaeschke, Hartmut
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171351/
https://ncbi.nlm.nih.gov/pubmed/24905542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.05.010
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