XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development

Sex chromosome dosage compensation is essential in most metazoans, but the developmental timing and underlying mechanisms vary significantly, even among placental mammals. Here we identify human-specific mechanisms regulating X chromosome activity in early embryonic development. Single-cell RNA sequ...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Vallot, Céline, Patrat, Catherine, Collier, Amanda J., Huret, Christophe, Casanova, Miguel, Liyakat Ali, Tharvesh M., Tosolini, Matteo, Frydman, Nelly, Heard, Edith, Rugg-Gunn, Peter J., Rougeulle, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Short Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222720/
https://ncbi.nlm.nih.gov/pubmed/27989768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.014
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