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The region 3′ to Xist mediates X chromosome counting and H3 Lys-4 dimethylation within the Xist gene

A counting process senses the X chromosome/autosome ratio and ensures that X chromosome inactivation (XCI) initiates in the female (XX) but not in the male (XY) mouse embryo. Counting is regulated by the X-inactivation centre, which contains the Xist gene. Deleting 65 kb 3′ to Xist in XO embryonic s...

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Detalhes bibliográficos
Main Authors: Morey, Céline, Navarro, Pablo, Debrand, Emmanuel, Avner, Philip, Rougeulle, Claire, Clerc, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271805/
https://ncbi.nlm.nih.gov/pubmed/14749728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600071
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