XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development

Sex chromosome dosage compensation is essential in most metazoans, but the developmental timing and underlying mechanisms vary significantly, even among placental mammals. Here we identify human-specific mechanisms regulating X chromosome activity in early embryonic development. Single-cell RNA sequ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Stem Cell
Egile Nagusiak: Vallot, Céline, Patrat, Catherine, Collier, Amanda J., Huret, Christophe, Casanova, Miguel, Liyakat Ali, Tharvesh M., Tosolini, Matteo, Frydman, Nelly, Heard, Edith, Rugg-Gunn, Peter J., Rougeulle, Claire
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2017
Gaiak:
Short Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222720/
https://ncbi.nlm.nih.gov/pubmed/27989768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.014
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