XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development

Sex chromosome dosage compensation is essential in most metazoans, but the developmental timing and underlying mechanisms vary significantly, even among placental mammals. Here we identify human-specific mechanisms regulating X chromosome activity in early embryonic development. Single-cell RNA sequ...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Stem Cell
Main Authors: Vallot, Céline, Patrat, Catherine, Collier, Amanda J., Huret, Christophe, Casanova, Miguel, Liyakat Ali, Tharvesh M., Tosolini, Matteo, Frydman, Nelly, Heard, Edith, Rugg-Gunn, Peter J., Rougeulle, Claire
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2017
Teme:
Short Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222720/
https://ncbi.nlm.nih.gov/pubmed/27989768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.014
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