Altered Smooth Muscle Cell Force Generation as a Driver of Thoracic Aortic Aneurysms and Dissections

The importance of maintaining contractile function in aortic smooth muscle cells (SMCs) is evident by the fact that heterozygous mutations in the major structural proteins or kinases controlling contraction lead to the formation of aneurysms of the ascending thoracic aorta that predispose to life-th...

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Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Milewicz, Dianna M., Trybus, Kathleen M., Guo, Dongchuan, Sweeney, H. Lee, Regalado, Ellen, Kamm, Kristine, Stull, James T.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222685/
https://ncbi.nlm.nih.gov/pubmed/27879251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.303229
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