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Genes Predisposing to Thoracic Aortic Aneurysms and Dissections: Associated Phenotypes, Gene-Specific Management, and Genetic Testing

Thoracic aortic aneurysms leading to type A dissections (TAAD) are the major diseases affecting the aorta. A genetic predisposition for TAAD can occur as part of a genetic syndrome, as is the case for Marfan syndrome, due to mutations in FBN1, and Loeys-Dietz syndrome, which results from mutations i...

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Autori principali: Milewicz, Dianna M., Carlson, Alicia A., Regalado, Ellen S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615454/
https://ncbi.nlm.nih.gov/pubmed/20452526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccl.2010.01.017
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