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Therapeutics Targeting Drivers of Thoracic Aortic Aneurysms and Acute Aortic Dissections: Insights from Predisposing Genes and Mouse Models

Thoracic aortic diseases, including aneurysms and dissections of the thoracic aorta, are a major cause of morbidity and mortality. Risk factors for thoracic aortic disease include increased hemodynamic forces on the ascending aorta, typically due to poorly controlled hypertension, and heritable gene...

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Detalhes bibliográficos
Publicado no:Annu Rev Med
Main Authors: Milewicz, Dianna M., Prakash, Siddharth K., Ramirez, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499376/
https://ncbi.nlm.nih.gov/pubmed/28099082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-100415-022956
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