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Requirement for sphingosine 1–phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference

Angiogenesis, or new blood vessel formation, is critical for the growth and spread of tumors. Multiple phases of this process, namely, migration, proliferation, morphogenesis, and vascular stabilization, are needed for optimal tumor growth beyond a diffusion-limited size. The sphingosine 1–phosphate...

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Detalhes bibliográficos
Main Authors: Chae, Sung-Suk, Paik, Ji-Hye, Furneaux, Henry, Hla, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522258/
https://ncbi.nlm.nih.gov/pubmed/15489955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422716
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