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Requirement for sphingosine 1–phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference

Angiogenesis, or new blood vessel formation, is critical for the growth and spread of tumors. Multiple phases of this process, namely, migration, proliferation, morphogenesis, and vascular stabilization, are needed for optimal tumor growth beyond a diffusion-limited size. The sphingosine 1–phosphate...

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Autors principals: Chae, Sung-Suk, Paik, Ji-Hye, Furneaux, Henry, Hla, Timothy
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC522258/
https://ncbi.nlm.nih.gov/pubmed/15489955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422716
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