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Tracking the Activity of mTORC1 in Living Cells Using Genetically Encoded FRET-based Biosensor TORCAR

Mechanistic target of rapamycin complex 1 (mTORC1) responds to multiple distinct signals (growth factors, amino acids, stress, energy level) and coordinates cell growth and proliferation. The activity of mTORC1 is exquisitely regulated in response to distinct stimuli, however, the underlying molecul...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Protoc Chem Biol
Prif Awduron: Zhou, Xin, Li, Simin, Zhang, Jin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222552/
https://ncbi.nlm.nih.gov/pubmed/27925667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpch.11
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