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Tracking the Activity of mTORC1 in Living Cells Using Genetically Encoded FRET-based Biosensor TORCAR
Mechanistic target of rapamycin complex 1 (mTORC1) responds to multiple distinct signals (growth factors, amino acids, stress, energy level) and coordinates cell growth and proliferation. The activity of mTORC1 is exquisitely regulated in response to distinct stimuli, however, the underlying molecul...
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| Veröffentlicht in: | Curr Protoc Chem Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5222552/ https://ncbi.nlm.nih.gov/pubmed/27925667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpch.11 |
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