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Tracking the Activity of mTORC1 in Living Cells Using Genetically Encoded FRET-based Biosensor TORCAR

Mechanistic target of rapamycin complex 1 (mTORC1) responds to multiple distinct signals (growth factors, amino acids, stress, energy level) and coordinates cell growth and proliferation. The activity of mTORC1 is exquisitely regulated in response to distinct stimuli, however, the underlying molecul...

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Detalhes bibliográficos
Publicado no:Curr Protoc Chem Biol
Main Authors: Zhou, Xin, Li, Simin, Zhang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222552/
https://ncbi.nlm.nih.gov/pubmed/27925667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpch.11
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