Deletion of hyaluronan synthase 3 inhibits neointimal hyperplasia

OBJECTIVE: Hyaluronan (HA) is a polymeric glucosaminoglycan that forms a provisional extracellular matrix in diseased vessels. HA is synthesized by three different HA-synthases (HAS1, -2, -3). Aim of this study was to unravel the role of the HAS3 isoenzyme during experimental neointimal hyperplasia....

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Kiene, Lena S., Homann, Susanne, Suvorava, Tatsiana, Rabausch, Berit, Müller, Julia, Kojda, Georg, Kretschmer, Inga, Twarock, Sören, Dai, Guang, Deenen, René, Hartwig, Sonja, Lehr, Stefan, Köhrer, Karl, Savani, Rashmin C., Grandoch, Maria, Fischer, Jens W.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222548/
https://ncbi.nlm.nih.gov/pubmed/26586662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306607
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