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Deletion of hyaluronan synthase 3 inhibits neointimal hyperplasia

OBJECTIVE: Hyaluronan (HA) is a polymeric glucosaminoglycan that forms a provisional extracellular matrix in diseased vessels. HA is synthesized by three different HA-synthases (HAS1, -2, -3). Aim of this study was to unravel the role of the HAS3 isoenzyme during experimental neointimal hyperplasia....

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Kiene, Lena S., Homann, Susanne, Suvorava, Tatsiana, Rabausch, Berit, Müller, Julia, Kojda, Georg, Kretschmer, Inga, Twarock, Sören, Dai, Guang, Deenen, René, Hartwig, Sonja, Lehr, Stefan, Köhrer, Karl, Savani, Rashmin C., Grandoch, Maria, Fischer, Jens W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222548/
https://ncbi.nlm.nih.gov/pubmed/26586662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306607
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