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Cardiac fibroblast activation and hyaluronan synthesis in response to hyperglycemia and diet-induced insulin resistance

Diabetic patients are at a greater risk of heart failure due to diabetic cardiomyopathy and worsened outcome post-myocardial infarction. While the molecular mechanisms remain unclear, fibrosis and chronic inflammation are common characteristics of both conditions. Diabetes mellitus (types I and II)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gorski, Daniel J., Petz, Anne, Reichert, Christina, Twarock, Sören, Grandoch, Maria, Fischer, Jens W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372628/
https://ncbi.nlm.nih.gov/pubmed/30755628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36140-6
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