Rationale and study design for a phase I/IIa trial of anakinra in children with Kawasaki disease and early coronary artery abnormalities (The ANAKID Trial)

BACKGROUND: Although Kawasaki disease (KD) is the most common cause of acquired heart disease in children and may result in coronary artery aneurysms (CAA) with an attendant risk of myocardial infarction, there is no recommended therapy to halt progression of arterial wall damage and prevent aneurys...

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Bibliografiset tiedot
Julkaisussa:Contemp Clin Trials
Päätekijät: Tremoulet, Adriana H, Jain, Sonia, Kim, Susan, Newburger, Jane, Arditi, Moshe, Franco, Alessandra, Best, Brookie, Burns, Jane C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221485/
https://ncbi.nlm.nih.gov/pubmed/27080929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2016.04.002
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