Rationale and study design for a phase I/IIa trial of anakinra in children with Kawasaki disease and early coronary artery abnormalities (The ANAKID Trial)

BACKGROUND: Although Kawasaki disease (KD) is the most common cause of acquired heart disease in children and may result in coronary artery aneurysms (CAA) with an attendant risk of myocardial infarction, there is no recommended therapy to halt progression of arterial wall damage and prevent aneurys...

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Detalhes bibliográficos
Publicado no:Contemp Clin Trials
Main Authors: Tremoulet, Adriana H, Jain, Sonia, Kim, Susan, Newburger, Jane, Arditi, Moshe, Franco, Alessandra, Best, Brookie, Burns, Jane C
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221485/
https://ncbi.nlm.nih.gov/pubmed/27080929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2016.04.002
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