The nature and nurture of cell heterogeneity: accounting for macrophage gene-environment interactions with single-cell RNA-Seq

BACKGROUND: Single-cell RNA-Seq can be a valuable and unbiased tool to dissect cellular heterogeneity, despite the transcriptome’s limitations in describing higher functional phenotypes and protein events. Perhaps the most important shortfall with transcriptomic ‘snapshots’ of cell populations is th...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Wills, Quin F., Mellado-Gomez, Esther, Nolan, Rory, Warner, Damien, Sharma, Eshita, Broxholme, John, Wright, Benjamin, Lockstone, Helen, James, William, Lynch, Mark, Gonzales, Michael, West, Jay, Leyrat, Anne, Padilla-Parra, Sergi, Filippi, Sarah, Holmes, Chris, Moore, Michael D., Bowden, Rory
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219790/
https://ncbi.nlm.nih.gov/pubmed/28061811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3445-0
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