The nature and nurture of cell heterogeneity: accounting for macrophage gene-environment interactions with single-cell RNA-Seq

BACKGROUND: Single-cell RNA-Seq can be a valuable and unbiased tool to dissect cellular heterogeneity, despite the transcriptome’s limitations in describing higher functional phenotypes and protein events. Perhaps the most important shortfall with transcriptomic ‘snapshots’ of cell populations is th...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Wills, Quin F., Mellado-Gomez, Esther, Nolan, Rory, Warner, Damien, Sharma, Eshita, Broxholme, John, Wright, Benjamin, Lockstone, Helen, James, William, Lynch, Mark, Gonzales, Michael, West, Jay, Leyrat, Anne, Padilla-Parra, Sergi, Filippi, Sarah, Holmes, Chris, Moore, Michael D., Bowden, Rory
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219790/
https://ncbi.nlm.nih.gov/pubmed/28061811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3445-0
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